Where does digital health stand today—and what signals are shaping what comes next?
The speculative surge of the early 2020s has faded, giving way to a more grounded approach—one defined by measured investment, maturing infrastructure, and smarter integration across the healthcare ecosystem. From startups and payers to health systems and policymakers, leaders are now focused on scalable solutions, stronger ROI, and real-world impact.
So where does digital health stand today—and what signals are shaping what comes next?

Digital health in 2025 isn’t about chasing hype. It’s about doubling down on what works: evidence-based innovation, interoperable infrastructure, and real-world impact.
What’s Driving Growth: High-Impact Investment Areas
AI and Predictive Analytics continue to dominate conversations—and budgets. But the shift is toward targeted, clinical use cases: triage, diagnostics, care coordination, and population health management. Payers and providers are looking for platforms that not only predict but act, improving workflows and outcomes simultaneously.
Virtual Care Platforms have matured beyond basic telehealth. Hybrid care models, remote monitoring, and asynchronous communication tools are gaining traction. The winners in this space are focused on clinical integration and reimbursement alignment—not just convenience.
Digital Therapeutics are seeing renewed interest, particularly in behavioral health, chronic condition management, and oncology. As regulatory clarity improves and evidence bases grow, investors are watching closely.
Infrastructure Gets Real: The Foundation Behind the Innovation
For all the attention on shiny tech, healthcare IT infrastructure is where real transformation is happening. Cloud migration isn’t new, but the strategies are evolving—particularly among large systems balancing innovation with legacy system constraints. Interoperability via open APIs is no longer a nice-to-have; it’s a requirement. And with escalating cyber threats, security architecture is top-of-mind for every CIO.
Expect sustained investment in platforms that reduce vendor lock-in, support modular integrations, and offer enterprise-grade security. At HIMSS26, the Cybersecurity Command Center will spotlight the most advanced, enterprise-ready technologies shaping defense strategies.
Payers Double Down on Strategic Tech
Payers are no longer on the digital health sidelines. They’re investing heavily in tools that streamline operations and elevate the member experience.
Member experience platforms are being built to mirror consumer-grade digital interactions while capturing rich data for personalization and retention.
Risk adjustment and analytics tools help ensure accurate payments and early identification of costly trends.
Value-based care enablement is getting tech-first support: care navigation, real-time data exchange, and outcomes-based reimbursement models are driving demand.
Startups: Smarter Funding, Sharper Focus
The startup funding environment isn’t dead—but it is different. Early-stage investors are more selective, favoring clear value propositions, clinical validation, and experienced teams. Growth capital is still available but tied to milestone-based progress. M&A activity remains a viable path, particularly for startups solving infrastructure or data-related pain points.
Startups looking to break through in 2025 must prove more than innovation; they must prove traction. The Emerge Innovation Experience at HIMSS26 offers an elite platform to connect with investors, validate solutions, and gain real-world visibility.
Proving ROI in a Scrutinized Market
Health systems and payers want more than dashboards—they want results. ROI frameworks are evolving to evaluate not just cost savings, but also revenue impact and care quality.
Clinical outcome metrics must be embedded in product strategy from day one.
Operational efficiency needs to show up in reduced FTE hours, streamlined workflows, or faster decision-making.
Revenue impact can take many forms: increased reimbursements, reduced denials, or new service line potential.
Solutions that can tie outcomes to business cases will lead the next wave.
Partnerships That Power Progress
2025 is shaping up to be the year of strategic collaboration. Providers are forming more structured innovation partnerships with startups, often through venture arms or pilot programs. Payers are launching accelerator models and expanding their corporate venture reach. The emphasis is on long-term integration, not short-term pilots.
Startup Park at HIMSS26 is purpose-built for connecting emerging companies with providers and payers ready to invest in scalable, ecosystem-aligned innovation.
What matters now is whether a solution fits within a broader ecosystem—and whether it can scale within it.
What to Watch: Regulation, Readiness, and Roadblocks
As the FDA’s digital health framework continues to evolve, companies are adjusting to shifting expectations around software-as-a-medical-device oversight. Meanwhile, data privacy remains a moving target as state-level regulations add complexity. And payment models are in flux, particularly in Medicare Advantage and Medicaid.
At the same time, many organizations are struggling with implementation barriers: workforce training, clinician buy-in, and internal governance can stall even the most promising solutions. HIMSS26 offers targeted education tracks and preconference forums to help leaders navigate evolving compliance demands and drive adoption.
The Bottom Line: Invest in What Works
Digital health in 2025 isn’t about chasing hype. It’s about doubling down on what works: evidence-based innovation, interoperable infrastructure, and real-world impact. Whether you’re a payer, startup, or health system leader, the mandate is the same: build smarter, prove value, and scale sustainably.
Looking ahead to 2026? HIMSS26 will explore how emerging tech, evolving policy, and market-tested innovation are transforming healthcare delivery. Save the date and experience the next chapter of digital health, live.