The global healthcare IT market is projected to grow from $94.5 billion in 2021 to $172.3 billion by 2026, driven by accelerating innovation, rising consumer expectations, and the urgent need for more resilient systems. As the pace of digital transformation continues to intensify, healthcare leaders face a pivotal moment: prepare now, or risk falling behind the organizations redefining clinical and operational excellence.
The HIMSS 2026 Global Health Conference & Exhibition will bring these priorities into focus—showcasing the technologies, strategies, and partnerships shaping healthcare’s next era. These trends outline the areas that will demand executive attention in the lead-up to 2026.
AI and Machine Learning Integration
AI and machine learning are moving rapidly from pilots to core enterprise capabilities. The organizations that build strong governance and workforce readiness today will be the ones unlocking the greatest clinical and financial value tomorrow.
Key Developments
- Next-Generation Clinical Decision Support: AI models that support triage, diagnosis, care planning, and risk identification—driving consistency and speed.
- Enterprise Predictive Analytics: Tools that forecast capacity needs, readmissions, staffing requirements, and operational risk.
- AI-Enabled Diagnostics: Imaging and pathology solutions reducing diagnostic variation and improving throughput.
- Evolving Regulatory Guidance: Increasing global focus on transparency, validation, and responsible AI deployment.
- Enterprise Readiness: Success hinges on leadership alignment, clear governance, and workforce engagement.
Cybersecurity and Data Protection Evolution
Healthcare remains one of the most heavily targeted industries for cybercrime. As threats escalate, cybersecurity resilience has become a strategic imperative—not just an IT concern.
Key Focus Areas
- Heightened Threat Environment: Ransomware, supply-chain compromises, and AI-driven attacks continue to intensify.
- Zero-Trust Architectures: Establishing identity-based security as the operational default.
- Global Privacy and Compliance Expansion: Increasing expectations across HIPAA, GDPR, and emerging state and international regulations.
- Ransomware Defense and Recovery: Segmentation, immutable backups, and workforce training are now baseline requirements.
- Resilient Infrastructure Planning: Ensuring systems maintain continuity under active cyber stress.
Explore Cybersecurity sessions.
Interoperability and Data Exchange
Interoperability will serve as the backbone of next-generation care delivery models. Improved data liquidity enables better outcomes, more efficient operations, and stronger patient engagement.
Trends to Watch
- Accelerated FHIR Adoption: API-enabled exchange is becoming foundational for modern interoperability.
- Modernized Health Information Exchanges: Real-time, event-driven architecture is replacing manual and batch-based sharing.
- API-First Ecosystems: Organizations are moving toward modular platforms that support rapid innovation and vendor flexibility.
- Patient Data Portability: Heightened emphasis on giving patients meaningful access to their health information.
- Cross-System Integration: Persistent gaps remain across legacy systems, requiring targeted investment.
Learn more about FHIR and data exchange.
Digital Patient Experience Transformation
The digital front door is now a strategic priority. Patients expect seamless, personalized, and accessible interactions across the entire care continuum.
Key Innovations
- Expansion of Virtual and Hybrid Care: Sophisticated telehealth, remote patient monitoring, and asynchronous care models.
- Next-Generation Patient Apps and Portals: Enhanced communication, scheduling, and record access.
- Personalized Care Delivery: Data-driven insights supporting tailored treatments and improved outcomes.
- Digital Therapeutics Integration: Evidence-based software becoming a standard part of chronic disease and behavioral health pathways.
- High-Impact Engagement Tools: Technologies that improve adherence, satisfaction, and care navigation.
Find digital transformation insight sessions.
Cloud Infrastructure and Edge Computing
Cloud and edge technologies are redefining healthcare’s technical foundation. Their combined impact allows organizations to scale, innovate, and operate with greater resilience.
Strategic Insights
- Accelerated Cloud Adoption: Organizations are modernizing clinical, administrative, and analytic systems to achieve agility and cost efficiency.
- Edge Computing at the Point of Care: Powering real-time monitoring, device connectivity, and low-latency analytics.
- Hybrid Architectures: Blending public and private cloud to balance performance, security, and regulatory compliance.
- Data Sovereignty and Localization: Increasingly critical for global organizations.
- Performance and Uptime Optimization: Demand for fault tolerance and high availability continues to grow.
Find sessions on cloud infrastructure and edge computing.
Workforce Technology and Digital Skills
Digital transformation is only as strong as the workforce behind it. Leaders must prioritize modern tools, training, and change-management strategies to support adoption and long-term sustainability.
Preparation Areas
- Modern Workflow Tools: Reducing administrative burden and enhancing care team efficiency.
- Automation and RPA: Streamlining repetitive processes to free staff for higher-value work.
- Comprehensive Training and Upskilling: Ensuring competency with new digital platforms and data workflows.
- Digital Literacy Investment: Building baseline proficiency across all roles.
- Workforce Productivity and Well-Being: Leveraging analytics to optimize staffing and support retention.
Find sessions to support workforce technology and digital skills.
Prepare for What’s Ahead With HIMSS 2026
To navigate the shifts ahead, healthcare leaders must invest in the technologies, strategies, and teams that will define the future of care. The HIMSS 2026 Global Health Conference & Exhibition offers a premier opportunity to explore innovations firsthand, compare enterprise solutions, and engage with experts shaping the global health ecosystem.
Register Today and Choose Your Pass to customize your HIMSS26 journey to match your professional goals and secure your place at the forefront of healthcare innovation.
In support of improving patient care, this activity has been planned and implemented by Partners for Advancing Clinical Education (Partners) and HIMSS. Partners is jointly accredited by the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.